5-Bromosalicylaldehyde

5-Bromosalicylaldehyde is an aromatic compound containing both a bromine atom and an aldehyde group, with the molecular formula C₇H₅BrO₂. It appears as yellow to orange crystalline solid and is soluble in most organic solvents. Its molecular structure, which includes both a hydroxyl and an aldehyde functional group, makes it highly reactive and valuable in organic synthesis, pharmaceutical development, and coordination chemistry.

SPECIFICATIONS

Product Name 5-Bromosalicylaldehyde
CAS NO. 1761-61-1
EINECS No. 217-167-2
Molecular Formula C7H5BrO2
Molecular Mass 201.02
Assay 99%
Boiling Point( °C ) 247
Appearance(pending) Slightly yellow to yellow-beige Powder
Density(g/cm3 25 °C) 1.737

 

Applications by Fields

  1. Organic Synthesis
    • Ligand Synthesis: Acts as a building block for polydentate ligands in coordination chemistry.
    • Heterocycle Construction: Used to synthesize phenolic compounds, hydrazones, and Schiff bases, playing an important role in heterocyclic chemistry.
    • Intermediate Synthesis: Serves as a key intermediate in the synthesis of complex molecules containing hydroxyl and aldehyde functionalities.
  2. Pharmaceutical Chemistry
    • Lead Structure Modification: Functions as a scaffold for modifying drug candidates to enhance properties like lipophilicity and metabolic stability.
    • Drug Development: Involved in the synthesis of novel biologically active compounds with antibacterial, antiviral, anticancer, and antioxidant properties.
  3. Materials & Analytical Chemistry
    • Chemical Analysis: Utilized in colorimetric assays, spectrophotometric analysis, and selective ion recognition systems.
    • Photosensitive Materials: The presence of phenolic and aldehyde groups allows applications in designing light-responsive materials.
    • Metal Complexes: Used to prepare functional coordination compounds such as fluorescent probes or catalysts.

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